Betting Advice

Real Madrid vs Manchester City – Midweek moneymakers

Photo by Juan Manuel Serrano Arce/Getty Images

Last Updated: 10:35 GMT+2, Wed 10 December 2025. Written by Louis Kalinga

Two European heavyweights, Real Madrid and Manchester City, are all set to take center stage in matchday six of the UEFA Champions League on Wednesday night.

Record winners Real Madrid will host Manchester City in arguably the most anticipated match in round six. This fierce rivalry will be renewed after both sides meeting in the last four editions of the competition.

Fifth place Madrid have 12 points from their opening five games, two more than Man City who are in ninth place. All eyes will be on how Xabi Alonso will respond after a shock 2-0 defeat to Celta Vigo on Sunday evening.

Here we have a look at all key details of the match as well as the best betting option.

Team news

Eder Militao is the latest on the Madrid injury list after being forced off against Celta Vigo with a hamstring injury. He joins a long list of injured defenders as Trent Alexander-Arnold, Dean Huijsen, David Alaba and Dani Carvajal remain sidelined.

Toni Rudiger is set to start alongside Alvaro Carreras who is one booking away from suspension. The attacking line is fully fit with Jude Bellingham, Vinicius Jr and Rodrygo all set to start.

Matteo Kovacic and Rodri remain the only main injury concerns for the visiting City. Erling Haaland already has five goals in the CL and will lead the line, flanked by Phil Foden and Jeremy Doku.

Head-to-head and current form

Madrid’s 2-0 loss to Celta Vigo was their only defeat in the last five games, which features two draws as well.

Meanwhile, City have lost twice in that run but have since turned that around to win three straight games.

Current form:

Real Madrid – LWDWD

Man City – WWWLL

Previous results

Real Madrid 3-1 Man City (CL, Feb 19, 2025)

Man City 2-3 Real Madrid (CL, Feb 11, 2925)

Man City 1-2 Real Madrid (CL, April 17, 2024)

Real Madrid 3-3 Man City (CL, April 9, 2024)

Man City 4-0 Real Madrid (CL, May 17, 2023)

The takeaway

There have been 22 goals scored across the last five fixtures between these two sides, with goals and expected here as well. Madrid have a better home record than their visitors and are tipped to avoid defeat against a fairly inconsistent Pep Guardiola side. The best betting options for this game are Over 2.5 goals or Real Madrid to win or draw.

Photo: Juan Manuel Serrano Arce/Getty Images